Journal of Cancer Prevention

eISSN 2288-3657
pISSN 2288-3649

Comparison of GENEDIA® and GastroPanel® in the diagnosis of gastric diseases

Variable GENEDIA® GastroPanel®
Atrophic gastritis
AUC 0.649 0.666
P-value < 0.001 < 0.001
HpIgG cutoffa 0.46 18.31
Sensitivity (%) 72 74
Specificity (%) 57 55
Intestinal metaplasia
AUC 0.604 0.634
P-value < 0.001 < 0.001
HpIgG cutoffa 0.30 17.53
Sensitivity (%) 75 74
Specificity (%) 46 48
Gastric adenoma
AUC 0.553 0.541
P-value 0.030 0.097
HpIgG cutoffa 0.40 18.35
Sensitivity (%) 71 70
Specificity (%) 41 43
Gastric cancer
AUC 0.555 0.575
P-value 0.003 < 0.001
HpIgG cutoffa 0.21 19.33
Sensitivity (%) 74 66
Specificity (%) 36 48

Values are measured using GENEDIA® (GENEDIA Helicobacter pylori ELISA, Green Cross Co.) and GastroPanel® (GastroPanel ELISA, Biohit Oyj) kits. HpIgG, anti-H. pylori antibody immunoglobulin G; AUC, area under curve. aOptical density for GENEDIA®; enzyme-immunosorbent units for GastroPanel®.

J Cancer Prev 2024;29:148~156 https://doi.org/10.15430/JCP.24.024
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