JCP

eISSN 2288-3657
pISSN 2288-3649

Table 1

Caricaceae plant constituents with cytotoxic effects on cancer cell growth

Caricaceae plant constituent	Phytochemical	Treatment	References
Papaya juice (0.28–28 mg/mL)	Lycopene	Pure lycopene extracted (3–30 g/mL) Colon cancer: 10 μM Breast cancer: 3.5 μM (48 h) 1 μM (48 h) 5 μM (48 h)	[12,27]
Extract of papaya seed or pulp (0.1–100 g/mL)	BITC	Pure BITC (10 M) Treatment: 6.5–12 μmol	[7,27]
Caricaceae plant	Quercetin	25 μM	[12]
Leaves	α-Tocopherol	2.5 ± 0.4 μg/mL	[1,12]
Caricaceae plant	Resveratrol	10–50 μM	[2]
Caricaceae plant	PEITC	10 μmol	[7]
Shoot	Isoflavone	40,000 μg/day for 3–6 weeks	[1,7]
Caricaceae plant	Piperlongumine	100,000–300,000 μg/kg	[7]

BITC, benzyl isothiocyanate; PEITC, phenethyl isothiocyanate.

J Cancer Prev 2024;29:58~68 https://doi.org/10.15430/JCP.24.020