Journal of Cancer Prevention

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Fig. 5.

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Fig. 5. Dendropanax morbifera Leveille extract (DME) regulated the PI3K/AKT/mTOR signaling pathway.
(A) The expression levels of proteins related to the PI3K/AKT/mTOR signaling pathway were determined using western blotting after treating SK-Hep1 cells with 0, 10, 20, or 40 µg/mL DME for 24 hours. (B) Band intensity was normalized using a total form protein. (C) Cells were treated with 0 or 40 µg/mL DME and the AKT inhibitor LY294002, and the levels of p-AKT were assessed by western blotting analysis. Band intensities were normalized to total AKT. β-actin was used as an internal control. Values indicate the mean ± SD. *P < 0.05, **P < 0.01 as shown by the Student’s t-test.
J Cancer Prev 2023;28:185~193
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