Fig. 5. Predictive functional profiling of microbial communities, based on the Kyoto Encyclopedia of Genes and Genomes (KEGG) database, regarding metabolism related to carbohydrate, amino acid, lipid, nucleotide, and energy. Panels (A) and (B) represent male (M) and female (F) data, respectively. Panel (C) illustrates module M00053, which is the module about deoxyribonucleotide biosynthesis (ADP/GDP/CDP/UDP→dATP/dGTP/dCTP/dUTP), the significantly different modules for both sexes are shown in the scatter graph. Panels (D) and (E) depict predictive functional profiling of microbial communities through the KEGG orthology database for males and females, respectively. Panel (F) focuses on K02073, which is the gene encoding D-methionine transport system substrate-binding protein, are shown in the scatter graph with both sexes. WAS, water avoidance stress; CON, control.