Journal of Cancer Prevention

eISSN 2288-3657
pISSN 2288-3649

Concordance between IHC and endpoint RT-PCR based on molecular subtypes
IHC based Endpoint RT-PCR based κ value OPA
Luminal-A Luminal-B HER2+ TNBC
Luminal-A 19 (61.3) 4 (12.9) 0 (0.0) 8 (25.8) 0.200* 56.1 (23/41)
Luminal-B 2 (28.6) 3 (42.9) 1 (14.3) 1 (14.3)
HER2+ 0 (0.0) 1 (14.3) 0 (0.0) 0 (0.0)
TNBC 1 (50.0) 0 (0.0) 0 (0.0) 1 (50.0)
Total 22 (53.7) 8 (19.5) 1 (2.4) 10 (24.4)

Values are presented as number (%) or % (number/number). IHC, immunohistochemistry; OPA, overall percent agreement; RT-PCR, reverse transcription PCR; TNBC, triple negative breast cancer; HER2, human epidermal growth factor receptor 2; +, positive. The sum of the percentages does not equal 100% because of rounding. *P < 0.05.

J Cancer Prev 2023;28:64~74 https://doi.org/10.15430/JCP.2023.28.2.64
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