Journal of Cancer Prevention

eISSN 2288-3657
pISSN 2288-3649

Hazard ratios (HRs) and 95% confidence intervals (CIs) for colorectal cancer incidence according to coffee types

Coffee types
None Black Sugar 3-in-1
Men (n = 39,380)
Number 4,807 4,727 3,984 25,302
Person-years 43,849.3 41,703.2 36,377.6 230,383.0
Colorectal cancer
No. of event 62 65 46 283
Crude HR 1.00 (reference) 1.26 (0.89–1.78) 0.94 (0.64–1.38) 0.95 (0.72–1.25)
aHRa 1.00 (reference) 1.21 (0.85–1.73) 0.91 (0.62–1.33) 0.93 (0.70–1.23)
Colon cancer
No. of event 38 38 27 145
Crude HR 1.00 (reference) 1.25 (0.79–1.96) 0.92 (0.56–1.51) 0.82 (0.57–1.17)
aHRa 1.00 (reference) 1.17 (0.74–1.84) 0.87 (0.53–1.42) 0.78 (0.54–1.13)
Rectal cancer
No. of event 24 27 19 138
Crude HR 1.00 (reference) 1.29 (0.74–2.23) 0.99 (0.54–1.80) 1.16 (0.75–1.80)
aHRa 1.00 (reference) 1.29 (0.74–2.24) 0.97 (0.53–1.78) 1.16 (0.75–1.81)
Women (n = 74,863)
Number 13,535 12,609 9,442 38,352
Person-years 125,161.0 110,570.0 87,901.5 353,231.0
Colorectal cancer
No. of event 80 79 64 231
Crude HR 1.00 (reference) 1.47 (1.07–2.01) 1.36 (0.98–1.89) 1.24 (0.96–1.61)
aHRa 1.00 (reference) 1.42 (1.03–1.95) 1.33 (0.95–1.85) 1.18 (0.91–1.53)
Colon cancer
No. of event 52 57 42 151
Crude HR 1.00 (reference) 1.69 (1.16–2.47) 1.40 (0.93–2.11) 1.28 (0.94–1.76)
aHRa 1.00 (reference) 1.66 (1.13–2.44) 1.39 (0.92–2.10) 1.22 (0.89–1.69)
Rectal cancer
No. of event 28 22 22 80
Crude HR 1.00 (reference) 1.07 (0.61–1.89) 1.27 (0.72–2.22) 1.16 (0.75–1.79)
aHRa 1.00 (reference) 1.02 (0.58–1.81) 1.21 (0.69–2.14) 1.11 (0.71–1.72)

Values are present as number only or HR (95% CI).

aHR, adjusted HR.

aAdjusted for education level (< 10 yr, 10–12 yr, > 12 yr, and missing), body mass index (< 18.5 kg/m2, 18.5–22.9 kg/m2, 23–24.9 kg/m2, ≥ 25 kg/m2, and missing), smoking status (non-smoker, ex-smoker, current smoker, and missing), alcohol consumption (non-drinker, ex-drinker, current drinker, and missing), regular exercise (no, yes, and missing), first-degree family history of colorectal cancer (no, yes, and missing), red and processed meat intake (g/d, continuous), vegetable and fruits intake (g/d, continuous), and energy intake (kcal/d, continuous).

J Cancer Prev 2022;27:229~238 https://doi.org/10.15430/JCP.2022.27.4.229
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