Journal of Cancer Prevention

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Fig. 2.

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Fig. 2. Cedrol induces G1 arrest and apoptosis in HT29 cells. (A) Cell cycle analysis of HT29 cells. Cells were treated with indicated concentrations of cedrol for 48 hours, stained with propidium iodide and analyzed by flow cytometry. DNA-fluorescence histogram of cell distribution is shown. (B) Cell cycle analysis data are presented as the mean ± standard deviation of triplicate experiments. *P < 0.05, **P < 0.01 vs. control. (C) Effects of cedrol on the expression of cell cycle-related proteins. Western blotting was performed using indicated antibodies and actin was used as an internal control. CDK2, cyclin-dependent kinase 2; pRB, retinoblastoma protein; p-pRB, phosphorylated pRB.
J Cancer Prev 2022;27:221~228 https://doi.org/10.15430/JCP.2022.27.4.221
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