Journal of Cancer Prevention

eISSN 2288-3657
pISSN 2288-3649
Fig. 2.

Download original image

Fig. 2. GGE03 inhibits pro-inflammatory cytokine gene expression in H. pylori-infected AGS cells. AGS cells were pretreated with GE and GGE03 at indicated concentrations for 1 hour, followed by co-culture with H. pylori (50 multiplicity of infection) for additional 3.5 hours. The effects of GE and GGE03 on the mRNA expression of IL-8 (A), TNF-α (B), IL-6 (C), and IL-1β (D) in AGS cells were analyzed by quantitative real-time PCR (qRT-PCR). 18S rRNA was used as an internal control for the expression of pro-inflammatory cytokines. Data are the mean ± SD. Statistical significance was analyzed by ANOVA. IL, interleukin; H. pylori, Helicobacter pylori; n.s., not significant. ***P < 0.001 compared to control; #P < 0.05, ##P < 0.01, and ###P < 0.001 compared to the H. pylori group.
J Cancer Prev 2021;26:289~297
© J Cancer Prev
© Korean Society of Cancer Prevention. / Powered by INFOrang Co., Ltd