Journal of Cancer Prevention

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Fig. 2.

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Fig. 2. Relationship between BCAAs oxidation and diet. Intracellular BCAA oxidation is dependent on a constellation process manipulated by several states of dietary availability; after a meal, fasting, starvation and severe starvation. BCAAs oxidation increases after a meal but falls in a fasting state. BCAA oxidation increases in the liver during starvation and is primarily driven by gluconeogenic precursors in the TCA cycle. In severe starvation, BCAAs oxidation falls, likely to preserve essential amino acids for other metabolic functions critical for functional survival in the cytosol. BCAA, branched-chain amino acid; TCA, tricarboxylic acid.
J Cancer Prev 2021;26:237~243
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