Journal of Cancer Prevention

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Fig. 1.

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Fig. 1. TNF-α and poly (I:C) induce the expression of MCP-1 and CX3CL1 in pancreatic stellate cells (PSCs). Cells were treated with TNF-α at 10 ng/mL or poly (I:C) at 1 μg/mL for the indicated time periods. (A, B) mRNA expression was determined by real-time PCR analysis and normalized to that of glyceraldehyde-3-phosphate dehydrogenase (GAPDH). (C, D) Protein levels in the medium were determined by enzyme-linked immunosorbent assay (ELISA). Data are expressed as the mean ± SE. MCP-1, monocyte chemoattractant protein 1; poly (I:C), polyinosinic-polycytidylic acid; NAC, N-acetylcysteine; CX3CL1, chemokine C-X3-C motif ligand 1. *P < 0.05 vs. 0 hour.
J Cancer Prev 2021;26:195~206 https://doi.org/10.15430/JCP.2021.26.3.195
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