Fig. 1. Dose response effect of piceatannol (PIC) on cell viability of PC-3, VCaP, LNCaP, and 22Rv1 cells. Viability of (A) PC-3, (B) VCaP, (C) LNCaP, and (D) 22Rv1 prostate cancer cells after treatment with dimethyl sulfoxide (DMSO) or different concentrations of PIC for 24, 48, and 72 hours was determined by the trypan blue dye exclusion assay as described in Materials and Methods. The results are expressed as mean ± SD (n = 3). Significantly different (*P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001) compared with corresponding DMSO-treated control by one-way analysis of variance followed by Dunnnett’s test. The experiments were repeated twice with consistent results. Representative data from one such experiment is shown.

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