Journal of Cancer Prevention

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Fig. 2.

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Fig. 2. Effect of white-fleshed peach extracts (WFPE) on chronic nicotine-induced nephrotoxicity and hepatotoxicity in mice. Nicotine (5 mg/kg body weight [BW]) and/or WFPE (250 mg/kg BW or 500 mg/kg BW) were administered to mice (n = 6) once daily for 5 weeks. The control mice (n = 6) received saline alone. (A) The serum blood urea nitrogen (BUN) and creatinine levels were measured using commercially available kits for analysis of nephrotoxicity. (B) The serum levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were analyzed as evidence of hepatotoxicity. Data are expressed as mean ± SEM (n = 6 per group). #P < 0.05 versus control group; *P < 0.05 versus nicotine group.
Journal of Cancer Prevention 2017;22:22~32
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