Journal of Cancer Prevention : pISSN 2288-3649 / eISSN 2288-3657

Table. 3.

Table. 3.

Occurrence of second malignant neoplasm (SMN) according to the risk groups (n = 176)

Kind of SMN Risk group 1 (n = 79) Risk group 2 (n = 36) Risk group 3 (n = 61) P-value
Colon 0 (0) 2 (5.6) 3 (4.9) 0.086d
Stomach 4 (5.1) 4 (11.1) 0 (0) 0.024d
Kidney 2 (2.5) 1 (2.8) 1 (1.6) > 0.99d
Prostate 1 (1.3) 2 (5.6) 1 (1.6) 0.419d
Lung 0 (0) 2 (5.6) 1 (1.6) 0.091d
Thyroid 2 (2.5) 0 (0) 0 (0) 0.687d
Esophagus 0 (0) 1 (2.8) 0 (0) 0.205d
Head and Neck 1 (1.3) 0 (0) 0 (0) > 0.99
Hepatobiliary 0 (0) 0 (0) 1 (1.6) 0.551d
Hematology 1 (1.3) 0 (0) 1 (1.6) > 0.99
Any kind of SMN 10 (12.7) 11 (30.6) 6 (9.8) 0.016

Values are presented as number (%).

Risk group 1 includes the individuals who meet the criteria of National Lung Screening Trial (NLST): Age 55–74 years and ≥ 30 pack-year history of smoking and smoking cessation < 15 years.
Risk group 2 includes the individuals who would not meet the NLST criteria but are possibly related to the similar risk to those of NLST cohort: Age 50 years and ≥ 20 pack-year history of smoking and additional risk factors that increase the 6-year risk of lung cancer (PLCOM2012 [Prostate, Lung, Colorectal, and Ovarian Cancer Screening model] ≥ 0.0151).
Risk group 3 includes the individuals without risk factors, classified as moderate to low risk group.
These values were analyzed using Fisher’s exact tests.

J Cancer Prev 2019;24:48-53 https://doi.org/10.15430/JCP.2019.24.1.48
© 2019 J Cancer Prev