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Table. 3.

Table. 3.

Unadjusted and multivariate adjusted hazard ratios for overall survival and disease-free survival according to presence of family member with colorectal neoplasm

Variable 1st-degree FH of CRC 1st or 2nd-degree FH of CRC 1st-degree FH of colorectal neoplasm



No Yes No Yes No Yes
Overall mortality
 No. of events 348 14 346 16 346 16
 No. at risk 910 69 900 79 892 87
 Unadjusted HR (95% CI) 1 0.48 (0.28–0.82) 1 0.47 (0.28–0.77) 1 0.42 (0.26–0.70)
 Adjusted HR (95% CI) 1 0.52 (0.29–0.92) 1 0.59 (0.32–1.07) 1 0.49 (0.28–0.83)
Cancer recurrence or death from any cause (disease-free survival)
 No. of events 419 21 417 23 417 23
 No. at risk 910 69 900 79 892 87
 Unadjusted HR (95% CI) 1 0.59 (0.38–0.92) 1 0.56 (0.37–0.85) 1 0.49 (0.33–0.75)
 Adjusted HR (95% CI) 1 0.68 (0.42–1.09) 1 0.65 (0.41–1.02) 1 0.57 (0.36–0.91)

FH, family history; CRC, colorectal cancer; HR, hazard ratio.

J Cancer Prev 2019;24:1-10 https://doi.org/10.15430/JCP.2019.24.1.1
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