Journal of Cancer Prevention : pISSN 2288-3649 / eISSN 2288-3657

Table. 1.

Table. 1.

Baseline characteristics by family history of colorectal cancer

Characteristic First-degree family history of colorectal cancer P-value

No (n = 910) Yes (n = 69)
Age (yr) 59.7 (14–90) 57.5 (34–75) 0.14
Sex (male) 557 (61.2) 37 (53.6) 0.21
Body mass index (kg/m2) 23.5 (15.8–37.0) 23.5 (17.7–31.0) 0.29
ECOG PS 0.21
 0 749 (79.5) 54 (77.1)
 1–2 193 (20.5) 16 (22.9)
Current smoking 133 (14.6) 12 (17.4) 0.53
Alcohol 0.71
 None 601 (66.3) 45 (65.2)
 < 1 drink/d 249 (27.5) 18 (26.1)
 ≥ 1 drink/d 56 (6.2) 6 (8.7)
Site of primary tumor 0.23
 Right colon 194 (21.3) 19 (27.5)
 Left colon and rectum 716 (78.7) 50 (72.5)
Preoperative CEA (ng/mL) 3.00 (0–259) 2.00 (0–294) 0.61
Depth of invasion through bowel wall 0.15
 T1 and T2 105 (11.5) 12 (17.4)
 T3 and T4 805 (88.5) 57 (82.6)
Positive lymph nodes 0.25
 1–3 611 (67.1) 51 (73.9)
 ≥ 4 299 (32.9) 18 (26.1)
Tumor differentiation 0.86
 Well 89 (9.8) 7 (10.1)
 Moderate 730 (80.2) 54 (78.3)
 Poor 53 (5.8) 4 (5.8)
 Other 38 (4.2) 4 (5.8)
MSI status 0.08
 MSS 756 (92.6) 55 (85.9)
 MSI-L 34 (4.2) 4 (6.2)
 MSI-H 26 (3.2) 5 (7.8)

Values are presented as median (range) or number (%). ECOG, Eastern Cooperative Oncology Group; PS, performance status; CEA, carcinoembryonic antigen; MSI, microsatellite instability; MSS, microsatellite stable; MSI-L, MSI-low; MSI-H, MSI-high.

J Cancer Prev 2019;24:1-10 https://doi.org/10.15430/JCP.2019.24.1.1
© 2019 J Cancer Prev