Journal of Cancer Prevention : pISSN 2288-3649 / eISSN 2288-3657

Fig. 1.

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Fig. 1. General mechanisms for microbiota-related colon cancer. Bacteria and their products affect the gut permeability to antigen. Dietary substrates undergo bacterial metabolism to form potentially carcinogenic products such as NOCs and secondary bile acids. Accordingly, chronic inflammation and genotoxicity contribute to the colon tumorigenesis. NOCs, N-nitroso compounds. Adapted from Sun and Kato.15
Journal of Cancer Prevention 2018;23:117-25 https://doi.org/10.15430/JCP.2018.23.3.117
© 2018 Journal of Cancer Prevention