Journal of Cancer Prevention : pISSN 2288-3649 / eISSN 2288-3657

Fig. 1.

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Fig. 1. Schematic diagram for various RNA binding domains of RNA binding proteins (RBPs). RBP interacts with target mRNAs using unique RNA binding domain (RBD) or a combination of different RBDs. Depending on RBDs, each RBP has specificity and affinity for its target RNAs. Each domain is schematically depicted with different shapes and colors. Each RBP is presented depending on its size. dsRBM, double-stranded RNA binding motiff; hnRNP, heterogeneous nuclear ribonucleoprotein; RRM, RNA recognition motif; KH, K-homology; ZF-ZZ, zinc finger binding with two zinc ions; ZF-CCCH, zinc finger C-x8-C-x5-C-x3-H type; PKR, protein kinase R; hnRNPA1, heterogeneous ribonucleoprotein A1; HuR, Hu-antigen R; U2AF35, U2 small nuclear RNA auxiliary factor 35; SAM68, Src-associated protein in mitosis of 68 kDa; TTP, tristetraprolin; IGF2BPs, Insulin-like growth factor 2 mRNA-binding proteins; CPEB4, cytoplasmic polyadenylation element binding protein 4; AA, amino acids.
Journal of Cancer Prevention 2017;22:203-10 https://doi.org/10.15430/JCP.2017.22.4.203
© 2017 Journal of Cancer Prevention