Journal of Cancer Prevention

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Fig. 3. Pathway analysis of chromium toxicity. The analyzed data showed the potentials of genomic interaction, cellular processes, and diseases induced by exposure of chromium. 12 proteins, 5 cellular processes, 13 diseases, 2 small molecules and 1 functional class appeared in figure. MAPK, mitogen-activated protein kinase; AKT1, V-akt murine thymoma viral oncogene homolog 1; NFE2L2, nuclear factor, erythroid 2-like 2; CAT, catalase; IFNG, interferon gamma; CASP3, caspase 3, apoptosis-related cysteine peptidase; VEGFA, vascular endothelial growth factor A; TP53, tumor protein 53; BAX, B cell lymphoma 2 protein-associated X protein; ROS, reactive oxygen species.
Journal of Cancer Prevention 2015;20:232~240
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